Genetic and cellular plasticity of fungal pathogens

Genetic and cellular plasticity of fungal
pathogens during host adaptation

A hallmark of fungal pathogens is the ability to dynamically re-shape their growth and metabolism during the interaction with the host. The infection process is driven by rapid responses in cell signaling and gene expression as well as by long-term changes in genome structure. Understanding the molecular basis of this remarkable cellular and genetic plasticity is critical to control fungal disease.

Our lab combines genetics and cell biology with experimental evolution and large-scale phenotyping to study host adaptation in Fusarium oxysporum. This soil-inhabiting fungus causes vascular wilt disease in more than a hundred different crop plants, as well as life-threatening infections in immunocompromised humans. Our aim is to identify key mechanisms that are of general relevance for fungal pathogenicity and represent potential targets for antifungal control.

Latest news

We are happy to welcome back two former group members, María Victoria Aguilar Pontes and Sara Masachis Gelo. María Victoria obtained a María Zambrano Postdoctoral

A warm welcome to Avinash Kamble from Savitribai Phule Pune University, India, who joins our group for 3 months as a visiting Professor funded by

Congratulations to our colleague Manuel Sánchez López-Berges on his well-deserved promotion to Assistant Professor with tenure!

Where to find us:

Department of Genetics
Campus Rabanales
Edificio Gregor Mendel, 1st floor
14014 Córdoba

Phone: (+34) 957218981